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Modernity is juxtaposed with antiquity at this hotel. Forty Seven’s location—adjacent to the Forum and far from the chaos of the shopping district—and more affordable rates make this a good choice for travelers, especially those looking for a retreat. Near the quaint neighborhood of Trastevere, which filled with restaurants, wine bars and bakeries, just a block from Campidoglio Hill, the hotel comprises sixty-one rooms, including suites with private balconies. There’s also a rooftop terrace that overlooks the Temple of Vesta. And while guests have access to the hotel’s gym, the nearby Circo Massimo can’t be beat for a morning run. The hotel welcomes children and will arrange babysitters and family-friendly itineraries, including a kids’ guide to the city on its Web site. Rooms from $410.

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The first European property in the Waldorf Astoria crown, this hotel, at the northwestern end of the city, has the feel of a full-fledged resort. With fifteen acres of grounds, including a large pool near a grove of palm, umbrella pine, oak and magnolia trees, the Cavalieri, as it’s often called, offers a haven for when the city’s crowds become overwhelming. Don’t be put off by the exterior, which resembles a circa-1960 coastal condo complex; the hotel has every modern amenity. There’s even a three-Michelin-star restaurant, La Pergola, on the premises. If you are traveling as a family, the large guest rooms will give everyone more breathing space than at most city center hotels, and you’ll appreciate the children’s pool. There’s also a spa with water treatments and personal trainers. Rooms from $400.

What’s new: The hotel has begun lending guests MusicBox devices with various walking tours of the city.